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    A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

    Nature Chemical Biology, Published online: 07 October 2019; doi:10.1038/s41589-019-0365-8

    A phenotypic screen led to the identification of potent inhibitors of mouse BAK-driven apoptosis. The compounds interact with VDAC2 and stabilize its interaction with BAK, blocking apoptosis at an early stage to preserve long-term cell survival. …read more

    Source:: Nature Biochemistry


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