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    New tricks for an old drug

    New tricks for an old drug

    New tricks for an old drug, Published online: 08 October 2018; doi:10.1038/s41589-018-0137-x

    The prodrug dimethyloxalylglycine (DMOG) is a well-known tool compound used to study hypoxia. New findings reveal that DMOG also inhibits glutamine metabolism and can be exploited to selectively kill some cancer cells, highlighting important caveats when using DMOG for hypoxia studies. …read more

    Source:: Nature Biochemistry

          

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