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Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells

Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells

Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells, Published online: 09 July 2018; doi:10.1038/s41589-018-0098-0

Primordazine inhibits poly(A)-tail-independent noncanonical translation (PAINT) in early zebrafish embryos and in mammalian cells under select conditions, an effect mediated by deadenylated 3ʹ UTRs that results in ablation of primordial germ cells. …read more

Source:: Nature Biochemistry

      

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